Masashi Aoki Selected Research

THK5351

1/2021	18F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies.
11/2016	In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.

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Masashi Aoki Research Topics

Disease

45	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 07/2023 - 04/2003
31	Neuromyelitis Optica (Devic's Disease) 01/2024 - 01/2012
18	Disease Progression 11/2023 - 12/2002
14	Multiple Sclerosis 11/2023 - 10/2012
12	Optic Neuritis (Retrobulbar Neuritis) 01/2023 - 06/2013
11	Parkinson Disease (Parkinson's Disease) 12/2023 - 01/2011
9	Muscular Diseases (Myopathy) 11/2023 - 12/2005
8	Demyelinating Diseases (Demyelinating Disease) 01/2023 - 06/2013
7	Inclusion Body Myositis 12/2023 - 07/2014
7	Atrophy 01/2022 - 05/2004
7	Dysferlinopathy 01/2020 - 05/2005
7	Miyoshi myopathy 04/2013 - 12/2002
5	Encephalitis (Encephalitis, Rasmussen) 01/2023 - 02/2005
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 01/2011
5	Muscular Atrophy (Muscle Atrophy) 01/2020 - 05/2004
5	Muscle Weakness 06/2015 - 06/2007
4	Motor Neuron Disease (Primary Lateral Sclerosis) 03/2023 - 09/2010
4	Myasthenia Gravis 12/2019 - 11/2016
3	Inflammation (Inflammations) 01/2024 - 02/2020
3	Dystonia (Limb Dystonia) 12/2023 - 01/2013
3	Nonaka type Distal myopathy 10/2023 - 12/2005
3	Gliosis 03/2023 - 01/2018
3	Sarcoma (Soft Tissue Sarcoma) 03/2023 - 01/2017
3	Myelitis 01/2023 - 01/2014
3	COVID-19 01/2022 - 01/2021
3	Corticobasal Degeneration 11/2021 - 11/2016
3	Parkinsonian Disorders (Parkinsonism) 11/2021 - 11/2016
3	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 11/2021 - 01/2020
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 11/2016
3	Leukocytosis (Pleocytosis) 02/2020 - 08/2014
3	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2016 - 01/2012
3	Juvenile Amyotrophic Lateral Sclerosis 2 01/2016 - 10/2008
3	X-Linked Bulbo-Spinal Atrophy 05/2014 - 01/2006
3	type 2B Limb-girdle muscular dystrophy 04/2013 - 11/2005
3	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 04/2013 - 11/2005
3	Distal Myopathies (Distal Muscular Dystrophy) 09/2012 - 10/2004
2	Proteostasis Deficiencies 01/2024 - 12/2023
2	Body Weight (Weight, Body) 12/2023 - 03/2023
2	Wounds and Injuries (Trauma) 05/2023 - 01/2021
2	Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis) 01/2023 - 01/2022
2	Synucleinopathies 01/2023 - 08/2012
2	Vision Disorders (Hemeralopia) 01/2022 - 01/2012
2	Infections 01/2022 - 01/2021
2	Fatigue 01/2021 - 06/2015
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2021 - 12/2002
2	Nervous System Diseases (Neurological Disorders) 01/2021 - 01/2018
2	Aphasia (Dysphasia) 06/2020 - 01/2018
2	Encephalomyelitis (Myeloencephalitis) 01/2020 - 01/2012
2	Muscular Dystrophies (Muscular Dystrophy) 01/2020 - 01/2020
2	Neutral Lipid Storage Disease with Myopathy 01/2020 - 07/2014
2	Nausea 04/2019 - 06/2013
2	Respiratory Insufficiency (Respiratory Failure) 04/2019 - 01/2008
2	Hemorrhage 01/2019 - 01/2008

Drug/Important Bio-Agent (IBA)

17	AntibodiesIBA 07/2023 - 02/2005
17	Superoxide Dismutase-1IBA 01/2021 - 04/2003
15	Proteins (Proteins, Gene)FDA Link 03/2023 - 02/2005
15	DysferlinIBA 01/2020 - 12/2002
12	Myelin-Oligodendrocyte GlycoproteinIBA 01/2023 - 02/2014
9	AutoantibodiesIBA 12/2023 - 06/2013
9	Immunoglobulin G (IgG)IBA 01/2023 - 01/2009
8	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 11/2019 - 11/2007
7	SteroidsIBA 02/2024 - 01/2012
7	Complement System Proteins (Complement)IBA 01/2024 - 01/2013
7	SynucleinsIBA 12/2023 - 01/2011
7	Biomarkers (Surrogate Marker)IBA 12/2023 - 07/2013
7	Aquaporin 4IBA 02/2023 - 06/2013
5	CytokinesIBA 01/2024 - 08/2014
4	AcidsIBA 11/2023 - 01/2011
4	N-Acetylneuraminic Acid (Sialic Acid)IBA 11/2023 - 12/2014
4	EdaravoneIBA 07/2023 - 03/2011
4	Creatine Kinase (Creatine Phosphokinase)IBA 04/2013 - 05/2004
3	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2024 - 08/2019
3	Glucose (Dextrose)FDA LinkGeneric 08/2023 - 01/2018
3	Retinaldehyde (Retinal)IBA 01/2022 - 04/2016
3	Prednisolone (Predate)FDA LinkGeneric 04/2021 - 01/2018
3	bimagrumabIBA 01/2021 - 01/2019
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 05/2006
3	EnzymesIBA 04/2019 - 12/2014
3	Neuroprotective AgentsIBA 01/2019 - 07/2005
3	Corticotropin-Releasing HormoneIBA 01/2016 - 01/2012
2	Protein AggregatesIBA 01/2024 - 01/2022
2	Interleukin-6 (Interleukin 6)IBA 01/2024 - 08/2014
2	Botulinum Toxins (Botulinum Toxin)IBA 02/2023 - 01/2016
2	Antidepressive Agents (Antidepressants)IBA 02/2023 - 01/2019
2	ElectrolytesIBA 01/2023 - 01/2018
2	BNT162 VaccineIBA 01/2023 - 01/2021
2	ropinirole (Requip)FDA LinkGeneric 01/2023 - 12/2019
2	eculizumab FDA Link 12/2022 - 01/2021
2	THK5351IBA 01/2021 - 11/2016
2	Levodopa (L Dopa)FDA LinkGeneric 01/2021 - 07/2018
2	Intravenous Immunoglobulins (IVIG)FDA Link 01/2021 - 01/2009
2	Phosphotransferases (Kinase)IBA 09/2020 - 02/2019
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 07/2014
2	Riluzole FDA LinkGeneric 04/2019 - 06/2015

Therapy/Procedure

23	Therapeutics 11/2023 - 02/2005
4	Tracheostomy 01/2020 - 01/2008
3	Oral Administration 11/2023 - 01/2023
2	Activities of Daily Living (ADL) 02/2024 - 12/2013
2	Secondary Prevention 01/2023 - 01/2021
2	Thymectomy 12/2019 - 09/2019